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BDBM69467 7-(3-Methyl-thiophen-2-yl)-5-propyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester::7-(3-methyl-2-thienyl)-5-propyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester::7-(3-methyl-2-thiophenyl)-5-propyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester::MLS000762761::SMR000440057::cid_5769924::ethyl 7-(3-methylthiophen-2-yl)-5-propyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate

SMILES: CCCC1=Nc2ncnn2C(C1C(=O)OCC)c1sccc1C

InChI Key: InChIKey=PHXMKRLVZFPBMY-UHFFFAOYNA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 69467   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM69467
PNG
(7-(3-Methyl-thiophen-2-yl)-5-propyl-4,7-dihydro-[1...)
Show SMILES CCCC1=Nc2ncnn2C(C1C(=O)OCC)c1sccc1C
Show InChI InChI=1/C16H20N4O2S/c1-4-6-11-12(15(21)22-5-2)13(14-10(3)7-8-23-14)20-16(19-11)17-9-18-20/h7-9,12-13H,4-6H2,1-3H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair