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BDBM69589 3-chloranyl-N-[2-(2-chlorophenyl)-5-oxidanyl-4-oxidanylidene-chromen-8-yl]benzamide::3-chloro-N-[2-(2-chlorophenyl)-5-hydroxy-4-keto-chromen-8-yl]benzamide::3-chloro-N-[2-(2-chlorophenyl)-5-hydroxy-4-oxo-1-benzopyran-8-yl]benzamide::3-chloro-N-[2-(2-chlorophenyl)-5-hydroxy-4-oxochromen-8-yl]benzamide::MLS000879351::SMR000128953::cid_5314942

SMILES: Oc1ccc(NC(=O)c2cccc(Cl)c2)c2oc(cc(=O)c12)-c1ccccc1Cl

InChI Key: InChIKey=KYONJIWWABRGQD-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 69589   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM69589
PNG
(3-chloranyl-N-[2-(2-chlorophenyl)-5-oxidanyl-4-oxi...)
Show SMILES Oc1ccc(NC(=O)c2cccc(Cl)c2)c2oc(cc(=O)c12)-c1ccccc1Cl
Show InChI InChI=1S/C22H13Cl2NO4/c23-13-5-3-4-12(10-13)22(28)25-16-8-9-17(26)20-18(27)11-19(29-21(16)20)14-6-1-2-7-15(14)24/h1-11,26H,(H,25,28)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 8.74E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair