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BDBM69777 1,5-dimethyl-2,4-bis(oxidanylidene)-3-(phenylmethyl)thieno[2,3-d]pyrimidine-6-carboxylic acid::1,5-dimethyl-2,4-dioxo-3-(phenylmethyl)-6-thieno[2,3-d]pyrimidinecarboxylic acid::3-benzyl-1,5-dimethyl-2,4-dioxothieno[2,3-d]pyrimidine-6-carboxylic acid::3-benzyl-2,4-diketo-1,5-dimethyl-thieno[2,3-d]pyrimidine-6-carboxylic acid::MLS001215902::SMR000544866::cid_8073077

SMILES: Cc1c(sc2n(C)c(=O)n(Cc3ccccc3)c(=O)c12)C(O)=O

InChI Key: InChIKey=HJOIQFMNHBXJTE-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 69777   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM69777
PNG
(1,5-dimethyl-2,4-bis(oxidanylidene)-3-(phenylmethy...)
Show SMILES Cc1c(sc2n(C)c(=O)n(Cc3ccccc3)c(=O)c12)C(O)=O
Show InChI InChI=1S/C16H14N2O4S/c1-9-11-13(19)18(8-10-6-4-3-5-7-10)16(22)17(2)14(11)23-12(9)15(20)21/h3-7H,8H2,1-2H3,(H,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair