BDBM702 (2R,3R,4R,5R)-2,5-bis[(2-fluorophenyl)sulfanyl]-3,4-dihydroxy-N,N'-bis[(1S)-2-methyl-1-(methylcarbamoyl)propyl]hexanediamide::Diol-Based HIV-1 protease inhibitor 15::N1,N6-Di-[(1S)-2-methyl-1-(methylcarbamoyl)propyl]-(2R,3R,4R,5R)-2,5-di(2-fluorophenylsulfanyl)-3,4-dihydroxyhexanediamide
SMILES CNC(=O)[C@@H](NC(=O)[C@H](Sc1ccccc1F)[C@H](O)[C@@H](O)[C@@H](Sc1ccccc1F)C(=O)N[C@@H](C(C)C)C(=O)NC)C(C)C
InChI Key InChIKey=RRSJFIZKJZRETD-XOGRSFEHSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 702
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Stockholm University
Stockholm University
Affinity DataKi: 0.570nM ΔG°: -12.8kcal/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair