BDBM706992 US20240400537, Example EX-C-25

SMILES CN[C@]1(c2cccc(F)c2)CC[C@]2(CC1)CN(c1ncc(OC3CC3)cc1C)C(=O)N2

InChI Key InChIKey=DMSJMEUUBLMLFW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 706992   

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM706992(US20240400537, Example EX-C-25)
Affinity DataKi:  3.60nMAssay Description:The human μ-opioid (hMOP) receptor binding assay was performed as an filtration-based radio agonist binding assay. Cell membranes of transfected CHO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

TargetNociceptin receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM706992(US20240400537, Example EX-C-25)
Affinity DataKi:  7.10nMAssay Description:The human nociceptin (hNOP) receptor binding assay was performed as an filtration-based radio agonist binding assay. Cell membrane homogenates of tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent