BDBM709476 6-(1-(1-((1R,4R)-5- acryloyl-2,5- diazabicyclo[2.2.1]heptane- 2-carbonyl)piperidin-4- yl)-1H-pyrazol-4-yl)-4- methoxypyrazolo[1,5- a]pyridine-3-carbonitrile::US12180207, Example 5
SMILES C=CC(=O)N1C[C@H]2C[C@@H]1CN2C(=O)N1CCC(n2cc(-c3cc(OC)c4c(C#N)cnn4c3)cn2)CC1
InChI Key InChIKey=GNYIEOAKPDOPCF-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 709476
Affinity DataIC50: 5nMAssay Description:he potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Fluorescence (...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:FGFR3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:FGFR2 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:FGFR1 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:he potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Fluorescence (...More data for this Ligand-Target Pair