BDBM712678 US12195427, Compound 53

SMILES [H]/N=C(\c1ccc2ccccc2c1)/N

InChI Key InChIKey=URXJHZXEUUFNKM-UHFFFAOYSA-N

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 712678   

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandChemical structure of BindingDB Monomer ID 712678BDBM712678(US12195427, Compound 53)
Affinity DataKi: <1.00E+4nMAssay Description:The MASP-2 assay protocol was carried out as follows. Test compounds were serially diluted in DMSO and then 100 nL of each dilution was transferred t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetProthrombin(Human)
Omeros

US Patent
LigandChemical structure of BindingDB Monomer ID 712678BDBM712678(US12195427, Compound 53)
Affinity DataKi:  1.75E+4nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent