BDBM71302 US9546164, 374::US9694002, 374

SMILES CS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2CCN(CC2)S(=O)(=O)c2cccc(c2)C(F)(F)F)cc1F

InChI Key InChIKey=HFUQIJGZENHTPZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 71302   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM71302(US9546164, 374 | US9694002, 374)
Affinity DataIC50:  23.1nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 1/10/11/2/3/4/5/8/9 subunit alpha(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM71302(US9546164, 374 | US9694002, 374)
Affinity DataIC50:  23nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent