BDBM71390 US9546164, 448::US9694002, 447::US9694002, 448

SMILES COC[C@@H](N1CCC[C@H](C1)Oc1cc(F)c(cc1C1CC1)C(=O)NS(C)(=O)=O)c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=QMOLJXRAMAPQPQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 71390   

LigandPNGBDBM71390(US9694002, 448 | US9694002, 447 | US9546164, 448)
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM71390(US9694002, 448 | US9694002, 447 | US9546164, 448)
Affinity DataIC50: 10.5nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details
US Patent

LigandPNGBDBM71390(US9694002, 448 | US9694002, 447 | US9546164, 448)
Affinity DataIC50: 11nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
US Patent