BDBM71437 US9546164, 480::US9694002, 480
SMILES Fc1ccc(COC2CCN(Cc3cc(F)c(cc3C3CC3)C(=O)NS(=O)(=O)C3CC3)CC2)c(Cl)c1
InChI Key InChIKey=JBECBHNSFAXSII-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 71437
Affinity DataIC50: 21.8nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
TargetSodium channel protein type 1/10/11/2/3/4/5/8/9 subunit alpha(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 22nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair