BDBM714949 US20250026748, Compound 113::US20260022114, Compound 117

SMILES COc1cnc(C(F)F)cc1-c1cc(-c2ccn(C)n2)ncc1C(=O)Nc1nnc(C#CC2CC2)s1

InChI Key InChIKey=GSOUEPGHLLFNOU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 714949   

TargetDNA polymerase theta(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714949BDBM714949(US20250026748, Compound 113 | US20260022114, Compo...)
Affinity DataIC50: 0.530nMAssay Description:PolQ ATPase enzyme (1-894) at 0.5 nM is incubated with a 10-point concentration response of inhibitors for 15 min at rt in the following buffer: 50 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent

TargetDNA polymerase theta [1-894](Homo sapiens (Human))
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714949BDBM714949(US20250026748, Compound 113 | US20260022114, Compo...)
Affinity DataIC50: 0.530nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent

TargetDNA polymerase theta [1-894](Homo sapiens (Human))
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 714949BDBM714949(US20250026748, Compound 113 | US20260022114, Compo...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent