BDBM717018 N-[2-chloro-4-(trifluoromethyl)phenyl]-2-{6-ethyl-7-[(2S)-4-(5- hydroxy-6-methylpyrimidine-4-carbonyl)-2-methylpiperazin-1-yl]-2- [(2R)-2-(methoxymethyl)azetidin-1-yl]-8-oxo-5H,8H-pyrido[2,3- b]pyrazin-5-yl}acetamide::US20250034136, Compound I-189

SMILES CCc1c(N2CCN(C(=O)c3ncnc(C)c3O)C[C@@H]2C)c(=O)c2nc(N3CC[C@@H]3COC)cnc2n1CC(=O)Nc1ccc(C(F)(F)F)cc1Cl

InChI Key InChIKey=LNUGCHYGASJDNU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717018   

LigandPNGBDBM717018(N-[2-chloro-4-(trifluoromethyl)phenyl]-2-{6-ethyl-...)
Affinity DataIC50: 27.5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
6/5/2025
Entry Details
US Patent