BDBM717036 N-(2-chloro-4-(trifluoromethyl)phenyl)-2-(2-(dimethylamino)-6-ethyl- 7-(4-(5-hydroxy-6-methylpyrimidine-4-carbonyl)octahydro-1H- cyclopenta[b]pyrazin-1-yl)-8-oxopyrido[2,3-b]pyrazin-5(8H)- yl)acetamide (single stereoisomer, first eluting compound as stereoisomer 1, cis)::US20250034136, Compound I-208

SMILES CCc1c(N2CCN(C(=O)c3ncnc(C)c3O)[C@H]3CCC[C@H]32)c(=O)c2nc(N(C)C)cnc2n1CC(=O)Nc1ccc(C(F)(F)F)cc1Cl

InChI Key InChIKey=UOHLIJKHSOFATI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717036   

LigandPNGBDBM717036(N-(2-chloro-4-(trifluoromethyl)phenyl)-2-(2-(dimet...)
Affinity DataIC50: 300nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent