BindingDB logo
myBDB logout

BDBM71862 2-(1,3-dihydrobenzimidazol-2-ylidene)-3-keto-6-methyl-4-phthalimido-enanthonitrile::2-(1,3-dihydrobenzimidazol-2-ylidene)-4-(1,3-dioxo-2-isoindolyl)-6-methyl-3-oxoheptanenitrile::2-(1,3-dihydrobenzimidazol-2-ylidene)-4-(1,3-dioxoisoindol-2-yl)-6-methyl-3-oxoheptanenitrile::4-[1,3-bis(oxidanylidene)isoindol-2-yl]-2-(1,3-dihydrobenzimidazol-2-ylidene)-6-methyl-3-oxidanylidene-heptanenitrile::MLS000109709::SMR000105648::cid_5310809

SMILES: CC(C)CC(N1C(=O)c2ccccc2C1=O)C(=O)C(C#N)c1nc2ccccc2[nH]1

InChI Key: InChIKey=IWIQZLJGZDSAQM-UHFFFAOYNA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 71862   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM71862
PNG
(2-(1,3-dihydrobenzimidazol-2-ylidene)-3-keto-6-met...)
Show SMILES CC(C)CC(N1C(=O)c2ccccc2C1=O)C(=O)C(C#N)c1nc2ccccc2[nH]1
Show InChI InChI=1/C23H20N4O3/c1-13(2)11-19(27-22(29)14-7-3-4-8-15(14)23(27)30)20(28)16(12-24)21-25-17-9-5-6-10-18(17)26-21/h3-10,13,16,19H,11H2,1-2H3,(H,25,26)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 1.48E+4n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Hsf1 protein


(Mus musculus)
BDBM71862
PNG
(2-(1,3-dihydrobenzimidazol-2-ylidene)-3-keto-6-met...)
Show SMILES CC(C)CC(N1C(=O)c2ccccc2C1=O)C(=O)C(C#N)c1nc2ccccc2[nH]1
Show InChI InChI=1/C23H20N4O3/c1-13(2)11-19(27-22(29)14-7-3-4-8-15(14)23(27)30)20(28)16(12-24)21-25-17-9-5-6-10-18(17)26-21/h3-10,13,16,19H,11H2,1-2H3,(H,25,26)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a>2.60E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2P55KXK
More data for this
Ligand-Target Pair