BDBM7238 (3Z)-3-(1H-imidazol-5-ylmethylidene)-5-methoxy-2,3-dihydro-1H-indol-2-one::3-(3H-Imidazol-4-ylmethylene)-5-methoxy-1,3-dihydro-indol-2-one::SU9516::cid_5289419::imidazole indolinone driv.

SMILES: COc1ccc2NC(=O)C(=Cc3cnc[nH]3)c2c1

InChI Key: InChIKey=QNUKRWAIZMBVCU-UHFFFAOYSA-N

Data: 16 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 7238   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4 (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4 (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 5 (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3 (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	7.4	22
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Platelet-derived growth factor receptor beta (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Interferon-induced, double-stranded RNA-activated protein kinase (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Probable global transcription activator SNF2L2 (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.12E+4	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	612	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 33 (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.73E+3	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	25
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Platelet-derived growth factor receptor beta (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	25
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Vascular endothelial growth factor receptor 2 (Human)	BDBM7238 (cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	25
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