BDBM7249 (3Z)-4-(2-hydroxyethyl)-3-({4-oxo-2H,4H,6H,7H-pyrano[3,4-c]pyrrol-1-yl}methylidene)-2,3-dihydro-1H-indol-2-one::pyrrollylactone indolinone driv. 15k
SMILES OCCc1cccc2NC(=O)\C(=C/c3[nH]cc4c3CCOC4=O)c12
InChI Key InChIKey=KJUURYWTEJSJCF-WQLSENKSSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 7249
Affinity DataIC50: 30nMpH: 7.4 T: 2°CAssay Description:For the assay, purified cdk/cyclin was added to polystyrene 96-well plates that were precoated with GST-Rb substrate in the presence of ATP. After i...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMT: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMT: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well microtit...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMT: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair