BDBM7252 (3Z)-3-({4-oxo-2H,4H,6H,7H-pyrano[3,4-c]pyrrol-1-yl}methylidene)-6-phenyl-2,3-dihydro-1H-indol-2-one::pyrrollylactone indolinone driv. 15n
SMILES O=C1Nc2cc(ccc2\C1=C\c1[nH]cc2c1CCOC2=O)-c1ccccc1
InChI Key InChIKey=IBBDZRORXASUQY-BOPFTXTBSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 7252
Affinity DataIC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:For the assay, purified cdk/cyclin was added to polystyrene 96-well plates that were precoated with GST-Rb substrate in the presence of ATP. After i...More data for this Ligand-Target Pair
Affinity DataIC50: 8.40E+3nMT: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMT: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well microtit...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair