BDBM7260 (3Z)-3-({4-oxo-2H,4H,5H,6H,7H-pyrrolo[3,4-c]pyridin-1-yl}methylidene)-4-(piperidin-4-yl)-2,3-dihydro-1H-indol-2-one::pyrrollylactam indolinone driv. 16l

SMILES O=C1Nc2cccc(C3CCNCC3)c2\C1=C\c1[nH]cc2c1CCNC2=O

InChI Key InChIKey=ORMCURCBAUGAQD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 7260   

LigandPNGBDBM7260((3Z)-3-({4-oxo-2H,4H,5H,6H,7H-pyrrolo[3,4-c]pyridi...)
Affinity DataIC50: 49nMpH: 7.4 T: 2°CAssay Description:For the assay, purified cdk/cyclin was added to polystyrene 96-well plates that were precoated with GST-Rb substrate in the presence of ATP. After i...More data for this Ligand-Target Pair
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Date in BDB:
1/11/2006
Entry Details Article
PubMed