BDBM7377 4-{7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol::6-phenyl[5H]pyrrolo[2,3-b]pyrazine (aloisine) 39::7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine::CHEMBL75680::aloisine A

SMILES: CCCCc1c([nH]c2nccnc12)-c1ccc(O)cc1

InChI Key: InChIKey=PRIGRJPRGZCFAS-UHFFFAOYSA-N

Data: 14 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 7377   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 5 activator 1 (Human)	BDBM7377 (CHEMBL75680 | aloisine A | 7-n-Butyl-6-(4-hydroxyp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3 (Human)	BDBM7377 (CHEMBL75680 | aloisine A | 7-n-Butyl-6-(4-hydroxyp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
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Cystic fibrosis transmembrane conductance regulator (Human)	BDBM7377 (CHEMBL75680 | aloisine A | 7-n-Butyl-6-(4-hydroxyp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	111	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM7377 (CHEMBL75680 | aloisine A | 7-n-Butyl-6-(4-hydroxyp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 alpha (Human)	BDBM7377 (CHEMBL75680 | aloisine A | 7-n-Butyl-6-(4-hydroxyp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cystic fibrosis transmembrane conductance regulator (Human)	BDBM7377 (CHEMBL75680 | aloisine A | 7-n-Butyl-6-(4-hydroxyp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
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Cystic fibrosis transmembrane conductance regulator (Human)	BDBM7377 (CHEMBL75680 | aloisine A | 7-n-Butyl-6-(4-hydroxyp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Baker's yeast)	BDBM7377 (CHEMBL75680 | aloisine A | 7-n-Butyl-6-(4-hydroxyp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 5 (Human)	BDBM7377 (CHEMBL75680 | aloisine A | 7-n-Butyl-6-(4-hydroxyp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Spiny starfish)	BDBM7377 (CHEMBL75680 | aloisine A | 7-n-Butyl-6-(4-hydroxyp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	30
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Glycogen synthase kinase-3 (Human)	BDBM7377 (CHEMBL75680 | aloisine A | 7-n-Butyl-6-(4-hydroxyp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 5 activator 1 (Human)	BDBM7377 (CHEMBL75680 | aloisine A | 7-n-Butyl-6-(4-hydroxyp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM7377 (CHEMBL75680 | aloisine A | 7-n-Butyl-6-(4-hydroxyp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM7377 (CHEMBL75680 | aloisine A | 7-n-Butyl-6-(4-hydroxyp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 (Human)	BDBM7377 (CHEMBL75680 | aloisine A | 7-n-Butyl-6-(4-hydroxyp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	646	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Rat)	BDBM7377 (CHEMBL75680 | aloisine A | 7-n-Butyl-6-(4-hydroxyp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	30
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Cyclin-dependent kinase 5 activator 1 [99-307] (Human)	BDBM7377 (CHEMBL75680 | aloisine A | 7-n-Butyl-6-(4-hydroxyp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	30
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