BDBM7402 (2 Z,3 E)-6-Bromoindirubin-3 -acetoxime::6-bromoindirubin-3 -acetoxime::[(3E)-2-[(3Z)-6-bromo-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-dihydro-1H-indol-3-ylidene]amino acetate::indirubin deriv. 8a

SMILES: CC(=O)ON=C1C(Nc2ccccc12)=C1C(=O)Nc2cc(Br)ccc12

InChI Key: InChIKey=MENDIXKFTXYTHJ-UHFFFAOYSA-N

Data: 4 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 7402   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Spiny starfish)	BDBM7402 ((2 Z,3 E)-6-Bromoindirubin-3 -acetoxime | [(3E)-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	7.2	30
TBA									Citation and Details
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Cyclin-dependent kinase 5 activator 1 [99-307] (Human)	BDBM7402 ((2 Z,3 E)-6-Bromoindirubin-3 -acetoxime | [(3E)-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	30
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Glycogen synthase kinase-3 beta (Porcine)	BDBM7402 ((2 Z,3 E)-6-Bromoindirubin-3 -acetoxime | [(3E)-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	30
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Aryl hydrocarbon receptor (Human)	BDBM7402 ((2 Z,3 E)-6-Bromoindirubin-3 -acetoxime | [(3E)-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3 (Human)	BDBM7402 ((2 Z,3 E)-6-Bromoindirubin-3 -acetoxime | [(3E)-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair