BDBM740777 N-(2-chloro-3-((3,5- dimethyl-4-oxo-3,4- dihydroquinazolin-6- yl)amino)-4- fluorophenyl)-2- azabicyclo[2.2.1] heptane-2-sulfonamide trifluoroacetate::US12303509, Example 81

SMILES Cc1c(Nc2c(F)ccc(NS(=O)(=O)N3CC4CCC3C4)c2Cl)ccc2ncn(C)c(=O)c12

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 740777   

LigandPNGBDBM740777(N-(2-chloro-3-((3,5- dimethyl-4-oxo-3,4- dihydroqu...)
Affinity DataIC50: 75nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged “tracer” bound to B-Raf via TR-FRET from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent