BDBM7461 5,7-dihydroxy-2-phenyl-4H-chromen-4-one::5,7-dihydroxy-2-phenyl-chromen-4-one::5,7-dihydroxyflavone::CHEMBL117::chrysin::cid_5281607

SMILES: c1ccc(cc1)C2=CC(=O)c3c(cc(cc3O2)O)O

InChI Key: InChIKey=RTIXKCRFFJGDFG-UHFFFAOYSA-N

Data: 21 KI  60 IC50  1 Kd  1 EC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 85 hits for monomerid = 7461   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2D6 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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3-oxoacyl-acyl-carrier protein reductase (malaria parasite P. falciparum)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B1 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Calmodulin-1 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1B1 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cytochrome P450 1A2 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cytochrome P450 1A1 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	153	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B1 [K65Q] (Bovine)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sialidase-2 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.90E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonyl reductase [NADPH] 1 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 5 activator 1 [99-307] (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	7.0	30
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Xanthine dehydrogenase/oxidase (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
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Aromatase (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Aromatase (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.91E+3	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2A6 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cytochrome P450 2B6 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cytochrome P450 1A1 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Integrase (Human immunodeficiency virus type 1)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Integrase (Human immunodeficiency virus type 1)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Integrase (Human immunodeficiency virus type 1)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Death-associated protein kinase 1 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Aromatase (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
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DNA gyrase A/A/B/B tetramer (Escherichia coli (strain K12))	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.96E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 0 group B member 1 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>6.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Neuraminidase (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Neuraminidase (Influenza A virus)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Neuraminidase (Influenza A virus)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Neuraminidase (Influenza A virus)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Xanthine dehydrogenase/oxidase (Bovine)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1B1 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
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Dipeptidyl peptidase 3 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.23E+5	n/a	n/a	n/a	n/a	7.4	37
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Steroidogenic factor 1 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>6.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Peroxisome proliferator-activated receptor gamma (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 10 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	37
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Mitogen-activated protein kinase 14 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.99E+4	n/a	n/a	n/a	n/a	n/a	37
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Glycogen synthase kinase-3 beta (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase pim-1 (Human)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	7.0	30
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Glycogen synthase kinase-3 beta (Rat)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	30
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Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Spiny starfish)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	7.0	30
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Cyclin homolog/dependent kinase 6 (Human-SaHV-2)	BDBM7461 (5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	7.0	30
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