BDBM7463 4,5-diphenyl-1H-pyrazolo[3,4-c]pyridazin-3-amine::Pyrazolopyridazine 1a::Pyrazolopyridazine deriv. 1a::pyrazolopyridazine deriv. 1

SMILES: Nc1n[nH]c2nnc(-c3ccccc3)c(-c3ccccc3)c12

InChI Key: InChIKey=NPHKXSDZIKFIRU-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 7463   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Spiny starfish)	BDBM7463 (Pyrazolopyridazine deriv. 1a | pyrazolopyridazine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	7.2	30
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Tyrosine-protein kinase Lck (Human)	BDBM7463 (Pyrazolopyridazine deriv. 1a | pyrazolopyridazine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM7463 (Pyrazolopyridazine deriv. 1a | pyrazolopyridazine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 alpha (Human)	BDBM7463 (Pyrazolopyridazine deriv. 1a | pyrazolopyridazine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	7.0	22
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Glycogen synthase kinase-3 beta (Human)	BDBM7463 (Pyrazolopyridazine deriv. 1a | pyrazolopyridazine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 (Human)	BDBM7463 (Pyrazolopyridazine deriv. 1a | pyrazolopyridazine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
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