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BDBM74639 4-(5-{[(4-ethoxyphenyl)amino]sulfonyl}-2,3-dihydro-1H-indol-1-yl)-4-oxobutanoic acid::4-[5-[(4-ethoxyphenyl)sulfamoyl]-2,3-dihydroindol-1-yl]-4-oxidanylidene-butanoic acid::4-[5-[(4-ethoxyphenyl)sulfamoyl]-2,3-dihydroindol-1-yl]-4-oxobutanoic acid::4-keto-4-[5-(p-phenetylsulfamoyl)indolin-1-yl]butyric acid::MLS000092470::SMR000028020::cid_3244118

SMILES: CCOc1ccc(NS(=O)(=O)c2ccc3N(CCc3c2)C(=O)CCC(O)=O)cc1

InChI Key: InChIKey=WBTPWIBUKRGAKJ-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 74639   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens (Human))
BDBM74639
PNG
(4-(5-{[(4-ethoxyphenyl)amino]sulfonyl}-2,3-dihydro...)
Show SMILES CCOc1ccc(NS(=O)(=O)c2ccc3N(CCc3c2)C(=O)CCC(O)=O)cc1
Show InChI InChI=1S/C20H22N2O6S/c1-2-28-16-5-3-15(4-6-16)21-29(26,27)17-7-8-18-14(13-17)11-12-22(18)19(23)9-10-20(24)25/h3-8,13,21H,2,9-12H2,1H3,(H,24,25)
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a>5.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair