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BDBM74800 1-[2-(3-Cyano-8-methyl-quinolin-2-ylamino)-ethyl]-3-(3-ethoxy-propyl)-thiourea::1-[2-[(3-cyano-8-methyl-2-quinolinyl)amino]ethyl]-3-(3-ethoxypropyl)thiourea::1-[2-[(3-cyano-8-methyl-2-quinolyl)amino]ethyl]-3-(3-ethoxypropyl)thiourea::1-[2-[(3-cyano-8-methyl-quinolin-2-yl)amino]ethyl]-3-(3-ethoxypropyl)thiourea::1-[2-[(3-cyano-8-methylquinolin-2-yl)amino]ethyl]-3-(3-ethoxypropyl)thiourea::MLS000557041::SMR000173448::cid_3221589

SMILES: CCOCCCNC(=S)NCCNc1nc2c(C)cccc2cc1C#N

InChI Key: InChIKey=WDSURKQHPYEBAU-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 74800   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens (Human))
BDBM74800
PNG
(1-[2-(3-Cyano-8-methyl-quinolin-2-ylamino)-ethyl]-...)
Show SMILES CCOCCCNC(=S)NCCNc1nc2c(C)cccc2cc1C#N
Show InChI InChI=1S/C19H25N5OS/c1-3-25-11-5-8-22-19(26)23-10-9-21-18-16(13-20)12-15-7-4-6-14(2)17(15)24-18/h4,6-7,12H,3,5,8-11H2,1-2H3,(H,21,24)(H2,22,23,26)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 3.20E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair