BDBM7491 (4Z)-4-(2-amino-5-oxo-3,5-dihydro-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8(1H)-one::(Z)-4-(2-amino-4-oxo-1H-imidazol-5(4H)-ylidene)-2-bromo-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8(1H)-one::(Z)-hymenialdisine::2-amino-5-[(4Z)-2-bromo-8-oxo-1H,4H,5H,6H,7H,8H-pyrrolo[2,3-c]azepin-4-ylidene]-4,5-dihydro-1H-imidazol-4-one::4-(2-Amino-4-oxo-2-imidazolidin-5-ylidene)-2-bromo-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one::4-(2-Amino-5-oxo-3,5-dihydro-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-c]azepin-8-one::4-(2-amino-4-oxo-1H-imidazol-5(4H)-ylidene)-2-bromo-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8(1H)-one::4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene]-2-bromo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-c]azepin-8-one::4-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4Z)-ylidene]-2-bromo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-c]azepin-8-one::CHEMBL361708::Hymenialdisine::Hymenialdisine, 1

SMILES: NC1=NC(=O)C(N1)=C1CCNC(=O)c2[nH]c(Br)cc12

InChI Key: InChIKey=ATBAETXFFCOZOY-UHFFFAOYSA-N

Data: 25 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 7491   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk2 (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Chk2 (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3 (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 5 (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Spiny starfish)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	7.2	30
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Casein kinase I isoform delta (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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Casein kinase II subunit alpha (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C beta type (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	73	n/a	n/a	n/a	n/a	7.2	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	7.2	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	37	n/a	n/a	n/a	n/a	7.2	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Rat)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	7.5	30
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Cyclin-dependent kinase 5 activator 1 [99-307] (Human)	BDBM7491 (4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	7.2	30
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