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BDBM75080 (Z)-4-(4-cyanophenyl)-2-keto-3-(2-quinolyl)but-3-enoic acid::(Z)-4-(4-cyanophenyl)-2-oxidanylidene-3-quinolin-2-yl-but-3-enoic acid::(Z)-4-(4-cyanophenyl)-2-oxo-3-(2-quinolinyl)-3-butenoic acid::(Z)-4-(4-cyanophenyl)-2-oxo-3-quinolin-2-ylbut-3-enoic acid::MLS001033775::SMR000385650::cid_6043656

SMILES: OC(=O)C(=O)C(=C/c1ccc(cc1)C#N)\c1ccc2ccccc2n1

InChI Key: InChIKey=YOLMTLQXWPYPOO-WJDWOHSUSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 75080   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens (Human))
BDBM75080
PNG
((Z)-4-(4-cyanophenyl)-2-keto-3-(2-quinolyl)but-3-e...)
Show SMILES OC(=O)C(=O)C(=C/c1ccc(cc1)C#N)\c1ccc2ccccc2n1
Show InChI InChI=1S/C20H12N2O3/c21-12-14-7-5-13(6-8-14)11-16(19(23)20(24)25)18-10-9-15-3-1-2-4-17(15)22-18/h1-11H,(H,24,25)/b16-11-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
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PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 1.25E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair