BDBM75080 (Z)-4-(4-cyanophenyl)-2-keto-3-(2-quinolyl)but-3-enoic acid::(Z)-4-(4-cyanophenyl)-2-oxidanylidene-3-quinolin-2-yl-but-3-enoic acid::(Z)-4-(4-cyanophenyl)-2-oxo-3-(2-quinolinyl)-3-butenoic acid::(Z)-4-(4-cyanophenyl)-2-oxo-3-quinolin-2-ylbut-3-enoic acid::MLS001033775::SMR000385650::cid_6043656

SMILES: OC(=O)C(=O)C(=C/c1ccc(cc1)C#N)\c1ccc2ccccc2n1

InChI Key: InChIKey=YOLMTLQXWPYPOO-WJDWOHSUSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 75080   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b (Homo sapiens (Human))	BDBM75080 ((Z)-4-(4-cyanophenyl)-2-keto-3-(2-quinolyl)but-3-e...) Show SMILES OC(=O)C(=O)C(=C/c1ccc(cc1)C#N)\c1ccc2ccccc2n1 Show InChI InChI=1S/C20H12N2O3/c21-12-14-7-5-13(6-8-14)11-16(19(23)20(24)25)18-10-9-15-3-1-2-4-17(15)22-18/h1-11H,(H,24,25)/b16-11-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q280513R
					More data for this Ligand-Target Pair