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BDBM75152 1-Allyl-4-hydroxy-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid p-tolylamide::1-allyl-2-hydroxy-4-keto-N-(p-tolyl)quinoline-3-carboxamide::2-hydroxy-N-(4-methylphenyl)-4-oxo-1-prop-2-enyl-3-quinolinecarboxamide::2-hydroxy-N-(4-methylphenyl)-4-oxo-1-prop-2-enylquinoline-3-carboxamide::MLS001205916::N-(4-methylphenyl)-2-oxidanyl-4-oxidanylidene-1-prop-2-enyl-quinoline-3-carboxamide::SMR000505051::cid_827970

SMILES: Cc1ccc(NC(=O)c2c(O)c3ccccc3n(CC=C)c2=O)cc1

InChI Key: InChIKey=OJHXNUZRYLRMNQ-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 75152   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens (Human))
BDBM75152
PNG
(1-Allyl-4-hydroxy-2-oxo-1,2-dihydro-quinoline-3-ca...)
Show SMILES Cc1ccc(NC(=O)c2c(O)c3ccccc3n(CC=C)c2=O)cc1
Show InChI InChI=1S/C20H18N2O3/c1-3-12-22-16-7-5-4-6-15(16)18(23)17(20(22)25)19(24)21-14-10-8-13(2)9-11-14/h3-11,23H,1,12H2,2H3,(H,21,24)
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PC sid
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Similars

PCBioAssay
n/an/an/an/a>5.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair