BindingDB logo
myBDB logout

BDBM75267 4-isoquinolin-2-ium-2-yl-5-[(phenylcarbonylhydrazinylidene)methyl]-1,3-thiazol-2-olate::5-[(benzoylhydrazinylidene)methyl]-4-(2-isoquinolin-2-iumyl)-2-thiazololate::5-[(benzoylhydrazinylidene)methyl]-4-isoquinolin-2-ium-2-yl-1,3-thiazol-2-olate::5-[(benzoylhydrazono)methyl]-4-isoquinolin-2-ium-2-yl-thiazol-2-olate::MLS001075266::SMR000646354::cid_4269389

SMILES: O=C(N\N=C\c1sc(=O)[n-]c1-[n+]1ccc2ccccc2c1)c1ccccc1

InChI Key: InChIKey=ZYORMRBBKNMWHI-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 75267   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens (Human))
BDBM75267
PNG
(4-isoquinolin-2-ium-2-yl-5-[(phenylcarbonylhydrazi...)
Show SMILES O=C(N\N=C\c1sc(=O)[n-]c1-[n+]1ccc2ccccc2c1)c1ccccc1
Show InChI InChI=1S/C20H14N4O2S/c25-19(15-7-2-1-3-8-15)23-21-12-17-18(22-20(26)27-17)24-11-10-14-6-4-5-9-16(14)13-24/h1-13H,(H-,21,22,23,25,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a>5.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair