BDBM760 Hydroxyethylene deriv. 11::tert-butyl N-[(2S,3S,5R)-5-benzyl-5-({1-[(2,3-dihydroxypropyl)carbamoyl]-2-methylbutyl}carbamoyl)-3-hydroxy-1-phenylpentan-2-yl]carbamate
SMILES CCC(C)C(NC(=O)[C@@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)Cc1ccccc1)C(=O)NCC(O)CO
InChI Key InChIKey=CNNKZGRBCPFNKW-IKGKUSMESA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 760
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataIC50: 0.150nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair