BDBM7646 CHEMBL102926::Imidazo[1,2-a]pyridine deriv. 6::N-{4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}-4-{2-methylimidazo[1,2-a]pyridin-3-yl}pyrimidin-2-amine

SMILES: CN(C)CC(O)COc1ccc(Nc2nccc(n2)-c2c(C)nc3ccccn23)cc1

InChI Key: InChIKey=VCPXSBULBDYRLT-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 7646   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM7646 (N-{4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	7.0	22
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Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM7646 (N-{4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	7.0	22
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Cyclin-dependent kinase 2 (Human)	BDBM7646 (N-{4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM7646 (N-{4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM7646 (N-{4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM7646 (N-{4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair