BDBM76986 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione::US11059801, Compound D-17::US9694015, Compound A

SMILES: Cc1nc2cccc(N)c2c(=O)n1C1CCC(=O)NC1=O

InChI Key: InChIKey=RSNPAKAFCAAMBH-UHFFFAOYSA-N

Data: 1 KI  10 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 76986   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-6 (Human)	BDBM76986 (3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	37
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Glyceraldehyde-3-phosphate dehydrogenase, cytosolic (Leishmania mexicana)	BDBM76986 (3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	37
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Interleukin-1 beta (Human)	BDBM76986 (3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	37
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Granulocyte-macrophage colony-stimulating factor (Human)	BDBM76986 (3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	37
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Mediator of DNA damage checkpoint protein 1 (Human)	BDBM76986 (3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	37
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C-C motif chemokine 3 (Human)	BDBM76986 (3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	37
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C-C motif chemokine 4 (Human)	BDBM76986 (3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	37
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Tumor necrosis factor (Human)	BDBM76986 (3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	37
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DNA damage-binding protein 1/Protein cereblon (Human)	BDBM76986 (3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	876	n/a	n/a	n/a	n/a	n/a	n/a
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Protein cereblon (Human)	BDBM76986 (3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Protein cereblon (Human)	BDBM76986 (3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Zinc finger protein Aiolos (Homo sapiens)	BDBM76986 (3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
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Protein cereblon (Human)	BDBM76986 (3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...) Show SMILES Show InChI	GoogleScholar	UniChem		1.67E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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