BDBM77092 CMX-157::CMX157::HDP-tenofovir::Tenofovir Exalidex::US12049474, Compound CMX157::hexadecyloxypropyl 9-(2-(phosphonomethoxy)propyl)adenine

SMILES: CCCCCCCCCCCCCCCCOCCCOP(O)(=O)CO[C@H](C)Cn1cnc2c(N)ncnc12

InChI Key: InChIKey=SCTJKHUUZLXJIP-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 77092   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein [588-1147,M628L,N654N,K657R,T802F,K807E] (HIV-1)	BDBM77092 (CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
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Gag-Pol polyprotein [588-1147,M628L,D654N,M771V,L797W,T802Y] (HIV-1)	BDBM77092 (CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1147,M628L,D654N,M771V,L797W,T802Y] (HIV-1)	BDBM77092 (CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
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Gag-Pol polyprotein [588-1147,V662I,F664L,F703Y,Q738M,M771V] (HIV-1)	BDBM77092 (CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Gag-Pol polyprotein [588-1147,M628L,T656S,M771V,L797W,T802Y] (HIV-1)	BDBM77092 (CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1147,K652R,M771V] (HIV-1)	BDBM77092 (CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM77092 (CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM77092 (CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Human)	BDBM77092 (CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM77092 (CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Human)	BDBM77092 (CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM77092 (CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair