BDBM771 3-[cyclopropyl(phenyl)methyl]-4-hydroxy-2H,5H,6H,7H,8H,9H,10H-cycloocta[b]pyran-2-one::CHEMBL16584::Cyclooctylpyranone 4::Cyclooctylpyranone 5d
SMILES Oc1c2CCCCCCc2oc(=O)c1C(C1CC1)c1ccccc1
InChI Key InChIKey=JHWCZVFBDHIFSP-UHFFFAOYSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 771
Affinity DataKi: 15nMAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
Affinity DataKi: 15nM ΔG°: -10.6kcal/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataKi: 96nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair