BDBM772 Benzamidine::CHEMBL79897::[amino(phenyl)methylidene]azanium::benzamidine deriv.::benzamidinium chloride

SMILES: c1ccc(cc1)C(=[NH2+])N

InChI Key: InChIKey=PXXJHWLDUBFPOL-UHFFFAOYSA-O

Data: 16 KI  1 IC50  4 ITC

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 772   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Human)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+5	n/a	n/a	n/a	n/a	8.0	22
TBA									Citation and Details
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Serine protease 1 (Bovine)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...) Show SMILES Show InChI	GoogleScholar	UniChem		4.80E+3	-7.18	n/a	n/a	n/a	n/a	n/a	7.4	22
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Urokinase-type plasminogen activator (Human)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...) Show SMILES Show InChI	GoogleScholar	UniChem		5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tryptase beta-2 (Human)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...) Show SMILES Show InChI	GoogleScholar	UniChem		2.00E+4	-6.34	n/a	n/a	n/a	n/a	n/a	7.4	22
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Serine protease 1 (Bovine)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10E+4	-6.31	n/a	n/a	n/a	n/a	n/a	7.4	22
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Prothrombin (Human)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...) Show SMILES Show InChI	GoogleScholar	UniChem		2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine protease 1 (Bovine)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...) Show SMILES Show InChI	GoogleScholar	UniChem		3.90E+4	-6.01	n/a	n/a	n/a	n/a	n/a	8.0	25
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Urokinase-type plasminogen activator (Human)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...) Show SMILES Show InChI	GoogleScholar	UniChem		9.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Urokinase-type plasminogen activator (Human)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...) Show SMILES Show InChI	GoogleScholar	UniChem		9.70E+4	-5.42	n/a	n/a	n/a	n/a	n/a	7.4	22
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Coagulation factor X (Human)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10E+5	-5.34	n/a	n/a	n/a	n/a	n/a	7.4	22
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Coagulation factor X (Human)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...) Show SMILES Show InChI	GoogleScholar	UniChem		1.65E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Urokinase-type plasminogen activator (Human)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...) Show SMILES Show InChI	GoogleScholar	UniChem		1.80E+5	-5.11	n/a	n/a	n/a	n/a	n/a	8.0	25
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Prothrombin (Human)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...) Show SMILES Show InChI	GoogleScholar	UniChem		3.20E+5	-4.72	n/a	n/a	n/a	n/a	n/a	7.4	22
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Urokinase-type plasminogen activator [179-431,I214M,N322A,S371A] (Human)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Complement C1s subcomponent (Human)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...) Show SMILES Show InChI	GoogleScholar	UniChem		6.03E+5	-4.40	n/a	n/a	n/a	n/a	n/a	8.05	25.5
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Tissue-type plasminogen activator (Human)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...) Show SMILES Show InChI	GoogleScholar	UniChem		7.50E+5	-4.22	n/a	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
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Tissue-type plasminogen activator (Human)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+6	>-4.09	n/a	n/a	n/a	n/a	n/a	8.0	25
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Activity Spreadsheet -- ITC Data from BindingDB

Found 4 hits for monomerid = 772

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
Trypsin (Bovine)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...)	GoogleScholar			-6.42	-2.37	-4.06	4.79	8	20.1
TBA					Details of this binding reaction
Trypsin (Bovine)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...)	GoogleScholar			-6.35	-1.84	-4.51	4.65	8	25.1
TBA					Details of this binding reaction
Trypsin (Bovine)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...)	GoogleScholar			-6.38	-1.29	-5.11	4.61	8	30
TBA					Details of this binding reaction
Trypsin (Bovine)	BDBM772 (Benzamidine | benzamidine deriv. | [amino(phenyl)m...)	GoogleScholar			-6.38	-0.719	-5.66	4.49	8	37.1
TBA					Details of this binding reaction