BDBM77617 4-methyl-2-(1-piperidinyl)quinoline::4-methyl-2-piperidin-1-yl-quinoline::4-methyl-2-piperidin-1-ylquinoline::4-methyl-2-piperidino-quinoline::ML204::VU0024172-3::cid_230710

SMILES Cc1cc(nc2ccccc12)N1CCCCC1

InChI Key InChIKey=USYRQXDHKXGTCK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 77617   

TargetShort transient receptor potential channel 4(Mus musculus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM77617(4-methyl-2-(1-piperidinyl)quinoline | 4-methyl-2-p...)
Affinity DataIC50:  2.63E+3nMAssay Description:Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetShort transient receptor potential channel 4(Mus musculus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM77617(4-methyl-2-(1-piperidinyl)quinoline | 4-methyl-2-p...)
Affinity DataIC50:  960nMAssay Description:Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced intracellular calciu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM77617(4-methyl-2-(1-piperidinyl)quinoline | 4-methyl-2-p...)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of HA-tagged mouse TRPC6 expressed in HEK293 cells assessed as reduction in acetylcholine-induced membrane potential by FLIPR membrane pot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 4(Mus musculus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM77617(4-methyl-2-(1-piperidinyl)quinoline | 4-methyl-2-p...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced current by QPatch cl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM77617(4-methyl-2-(1-piperidinyl)quinoline | 4-methyl-2-p...)
Affinity DataIC50:  840nMAssay Description:Inhibition of human recombinant acetylcholinesterase expressed in HEK-293 cells using AMTch as substrate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed