BDBM7781 4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione::NP 01139::TDZD-8::Thiadiazolidinone (TDZD) deriv. 8::US20230414581, Compound 1

SMILES: CN1C(=O)N(C(=O)S1)Cc2ccccc2

InChI Key: InChIKey=JDSJDASOXWCHPN-UHFFFAOYSA-N

Data: 20 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 7781   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Human)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3 (Human)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C zeta type (Rat)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta [7-25] (Rabbit)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	7.5	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
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NAD(+) hydrolase SARM1 (Human)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha (Bovine)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.5	37
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Protein kinase C beta type (Rat)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.5	37
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Beta-casein (Bovine)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.5	37
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Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM7781 (4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.5	37
TBA									Citation and Details
					More data for this Ligand-Target Pair