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BDBM78072 2-furanyl-[4-(5-phenyl-4-thieno[2,3-d]pyrimidinyl)-1-piperazinyl]methanone::2-furyl-[4-(5-phenylthieno[2,3-d]pyrimidin-4-yl)piperazino]methanone::4-[4-(2-furoyl)-1-piperazinyl]-5-phenylthieno[2,3-d]pyrimidine::MLS000534599::SMR000142036::cid_985331::furan-2-yl-[4-(5-phenylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl]methanone

SMILES: O=C(N1CCN(CC1)c1ncnc2scc(-c3ccccc3)c12)c1ccco1

InChI Key: InChIKey=HSJJWMKKIMXXCA-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 78072   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
TPA: Essential protein of the mitochondrial intermembrane space


(Saccharomyces cerevisiae S288c)
BDBM78072
PNG
(2-furanyl-[4-(5-phenyl-4-thieno[2,3-d]pyrimidinyl)...)
Show SMILES O=C(N1CCN(CC1)c1ncnc2scc(-c3ccccc3)c12)c1ccco1
Show InChI InChI=1S/C21H18N4O2S/c26-21(17-7-4-12-27-17)25-10-8-24(9-11-25)19-18-16(15-5-2-1-3-6-15)13-28-20(18)23-14-22-19/h1-7,12-14H,8-11H2
PDB
MMDB

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Similars

PCBioAssay
n/an/a 1.77E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2F18X6W
More data for this
Ligand-Target Pair