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BDBM78576 CIS-THIOTHIXENE::MLS000028463::SMR000058396::THIOTHIXENE::cid_941651::med.21724, Compound Thiothixene

SMILES: CN(C)S(=O)(=O)c1ccc2Sc3ccccc3\C(=C\CCN3CCN(C)CC3)c2c1

InChI Key: InChIKey=GFBKORZTTCHDGY-UHFFFAOYSA-N

Data: 48 KI 2 IC50 4 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 54 hits for monomerid = 78576
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Ubiquitin-conjugating enzyme E2 N (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (SARS-CoV)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	5.31E+3	n/a	n/a	n/a	n/a
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Orf1a protein (MERS-CoV)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	9.29E+3	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	0.630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	0.630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	0.660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Bovine)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Bovine)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	5.88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	11.0	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Rat)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Rat)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Rat)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Rat)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	50.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Rat)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Bovine)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	145	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Bovine)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Bovine)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	685	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Rat)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Rat)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A/1B/1D/2C (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Rat)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M4 (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Rat)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Rat)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M3 (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M1 (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Human)	BDBM78576 (MLS000028463 \| cid_941651 \| SMR000058396 \| CIS-THI...) Show SMILES Show InChI	GoogleScholar	UniChem	2.94E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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