BDBM7877 2-bromo-1-(4-chlorophenyl)ethan-1-one::Halomethyl Phenyl Ketone deriv. 25

SMILES Clc1ccc(cc1)C(=O)CBr

InChI Key InChIKey=FLAYZKKEOIAALB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7877   

TargetGlycogen synthase kinase-3 beta [7-25](Oryctolagus cuniculus (rabbit))
Instituto De Quimica Medica (Csic)

LigandPNGBDBM7877(2-bromo-1-(4-chlorophenyl)ethan-1-one | Halomethyl...)
Affinity DataIC50:  1.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Qui£?Mica Medica-Csic

Curated by ChEMBL
LigandPNGBDBM7877(2-bromo-1-(4-chlorophenyl)ethan-1-one | Halomethyl...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of GSK3beta using GS1 as substrate and [gamma-32P]ATP after 20 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Instituto De Qui£?Mica Medica-Csic

Curated by ChEMBL
LigandPNGBDBM7877(2-bromo-1-(4-chlorophenyl)ethan-1-one | Halomethyl...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of glycogen synthase kinase-3 beta (unknown origin) using GS-1 as substrate after 20 mins by scintillation counting analysis in presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed