BDBM7886 1-PIM::1-phenyl-1H-imidazole::1-phenylimidazole::CHEMBL275066::US9138393, 1-Phenyl- imidazole::US9144538, 1-Phenylimidazole

SMILES: c1cn(cn1)-c1ccccc1

InChI Key: InChIKey=SEULWJSKCVACTH-UHFFFAOYSA-N

Data: 2 KI  5 IC50  2 Kd  2 ITC

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 7886   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 3A4 (Human)	BDBM7886 (1-phenylimidazole | CHEMBL275066 | 1-phenyl-1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.25E+4	n/a	n/a	n/a	n/a	7.4	4
TBA									Citation and Details
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Cytochrome P450 3A4 (Human)	BDBM7886 (1-phenylimidazole | CHEMBL275066 | 1-phenyl-1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM7886 (1-phenylimidazole | CHEMBL275066 | 1-phenyl-1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.25E+4	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM7886 (1-phenylimidazole | CHEMBL275066 | 1-phenyl-1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 144 [31-434] (Mycobacterium tuberculosis)	BDBM7886 (1-phenylimidazole | CHEMBL275066 | 1-phenyl-1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.90E+5	n/a	n/a	n/a	7.0	n/a
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Serine/threonine-protein kinase mTOR (Human)	BDBM7886 (1-phenylimidazole | CHEMBL275066 | 1-phenyl-1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+7	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, inducible (Mouse)	BDBM7886 (1-phenylimidazole | CHEMBL275066 | 1-phenyl-1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, brain (Human)	BDBM7886 (1-phenylimidazole | CHEMBL275066 | 1-phenyl-1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		4.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Glutaminyl-peptide cyclotransferase (Human)	BDBM7886 (1-phenylimidazole | CHEMBL275066 | 1-phenyl-1H-imi...) Show SMILES Show InChI	GoogleScholar	UniChem		4.60E+6	-3.24	n/a	n/a	n/a	n/a	n/a	8.0	30
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Activity Spreadsheet -- ITC Data from BindingDB

Found 2 hits for monomerid = 7886

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
BDBM4	BDBM7886				-2.15	2.63	-4.78	1.57	10	24.9
TBA					Details of this binding reaction
BDBM11	BDBM7886				-1.91	7.40	-9.31	1.40	10	24.9
TBA					Details of this binding reaction