BindingDB PrimarySearch

BDBM79181 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566

SMILES: CN1CCN(CC1)CCCN2c3ccccc3Sc4c2cc(cc4)C(F)(F)F

InChI Key: InChIKey=ZEWQUBUPAILYHI-UHFFFAOYSA-N

Data: 71 KI 22 IC50 6 Kd

PDB links: 7 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 99 hits for monomerid = 79181
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Calmodulin-1 (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Calmodulin-1 (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Calmodulin-1 (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Protein kinase C zeta type (Rat)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (Rabbit)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Calmodulin-1 (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Lysozyme C-1 (Rat)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Beta-glucuronidase (Rat)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	0.532	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.04	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Ubiquitin-conjugating enzyme E2 N (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Pleiotropic ABC efflux transporter of multiple drugs (Baker's yeast)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Albumin (Rat)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Calmodulin (Bovine)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Calmodulin (Bovine)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
WD repeat-containing protein 48 (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Protein kinase C zeta type (Rat)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
NADPH oxidase 1 (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	0.410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	0.960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	0.960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Dopamine receptor D4 (Dog)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Bovine)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Bovine)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	2.63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Dopamine receptor D4 (Dog)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Emopamil-binding protein-like (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	3.98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM79181 (cid_2913535 \| TRIFLUOPERAZINE \| SMR000059133 \| MLS...) Show SMILES Show InChI	GoogleScholar	UniChem	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair

Displayed 1 to 50 (of 99 total ) | Next | Last >>