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BDBM79280 2-(2,4-diketo-7,7,9-trimethyl-1,3-diazaspiro[4.5]decan-3-yl)-N-(2-keto-1,3-dihydrobenzimidazol-5-yl)acetamide::MLS002165237::N-(2-oxidanylidene-1,3-dihydrobenzimidazol-5-yl)-2-[7,7,9-trimethyl-2,4-bis(oxidanylidene)-1,3-diazaspiro[4.5]decan-3-yl]ethanamide::N-(2-oxo-1,3-dihydrobenzimidazol-5-yl)-2-(7,7,9-trimethyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetamide::SMR001247604::cid_16297714

SMILES: CC1CC2(CC(C)(C)C1)NC(=O)N(CC(=O)Nc1ccc3[nH]c(=O)[nH]c3c1)C2=O

InChI Key: InChIKey=NMZXLFIUZLJVHZ-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 79280   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ubiquitin-conjugating enzyme E2 N


(Homo sapiens (Human))
BDBM79280
PNG
(2-(2,4-diketo-7,7,9-trimethyl-1,3-diazaspiro[4.5]d...)
Show SMILES CC1CC2(CC(C)(C)C1)NC(=O)N(CC(=O)Nc1ccc3[nH]c(=O)[nH]c3c1)C2=O
Show InChI InChI=1S/C20H25N5O4/c1-11-7-19(2,3)10-20(8-11)16(27)25(18(29)24-20)9-15(26)21-12-4-5-13-14(6-12)23-17(28)22-13/h4-6,11H,7-10H2,1-3H3,(H,21,26)(H,24,29)(H2,22,23,28)
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PC cid
PC sid
UniChem
PCBioAssay
n/an/a>2.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2X34VX0
More data for this
Ligand-Target Pair