BDBM7948 1-(3-Aminopropyl)-imidazole::3-(1H-imidazol-1-yl)propan-1-amine::Imidazole N-1 deriv. 9::US9138393, N-(3- Aminopropyl) imidazole::US9144538, N-(3-Aminopropyl) imidazole

SMILES NCCCn1ccnc1

InChI Key InChIKey=KDHWOCLBMVSZPG-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7948   

TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

LigandPNGBDBM7948(1-(3-Aminopropyl)-imidazole | 3-(1H-imidazol-1-yl)...)
Affinity DataKi:  4.10E+5nM ΔG°:  -4.70kcal/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Procter & Gamble

US Patent
LigandPNGBDBM7948(1-(3-Aminopropyl)-imidazole | 3-(1H-imidazol-1-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Cytochrome P450 is a large and diverse group of enzymes that catalyze the oxidation of organic substances. Some members of the CYP family contribute ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
The Procter & Gamble

US Patent
LigandPNGBDBM7948(1-(3-Aminopropyl)-imidazole | 3-(1H-imidazol-1-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:A commercially available P450-GLO Assay kit (Promega Corporation, Madison Wis.) is used to screen various compounds for CYP3A4A inhibition activity. ...More data for this Ligand-Target Pair
In DepthDetails US Patent