BDBM7966 2-(1H-imidazol-4-yl)ethan-1-amine::CHEMBL544208::CHEMBL90::Ceplene::Ergotidine::HISTAMINE DIHYDROCHLORIDE::Histamine::L-histamine::Peremin::[3H]histamine

SMILES: NCCc1cnc[nH]1

InChI Key: InChIKey=NTYJJOPFIAHURM-UHFFFAOYSA-N

Data: 75 KI  1 IC50  2 Kd  36 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 114 hits for monomerid = 7966   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	77	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	75	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	463	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	650	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	88	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rat)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	640	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Guinea pig)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	25.1	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	11.6	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Guinea pig)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Guinea pig)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Guinea pig)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Rat)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.17E+5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Guinea pig)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	191	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	191	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	25.1	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	12.0	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Guinea pig)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Guinea pig)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	191	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	12.9	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.12	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	25.1	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	15.8	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H2 receptor (Guinea pig)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.92E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine receptor H4 (Guinea pig)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H4 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hrh3 protein (Rat)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hrh3 protein (Rat)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hrh3 protein (Rat)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hrh3 protein (Rat)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H3 receptor (Human)	BDBM7966 ([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...) Show SMILES Show InChI	GoogleScholar	UniChem		6.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair