BDBM8054 2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 25::4-({4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl}amino)phenol::4-[4-(4-Methyl-2-methylaminothiazol-5-yl)pyrimidin-2-ylamino]phenol::4-[4-(4-Methyl-2-methylaminothiazol-5-yl)pyrimidin-2-ylamino]phenol, 6::CHEMBL47590

SMILES: CNc1nc(C)c(s1)-c1ccnc(Nc2ccc(O)cc2)n1

InChI Key: InChIKey=OTMLAWRVLMYMDF-UHFFFAOYSA-N

Data: 3 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 8054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Human)	BDBM8054 (4-[4-(4-Methyl-2-methylaminothiazol-5-yl)pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.5	20
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM8054 (4-[4-(4-Methyl-2-methylaminothiazol-5-yl)pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM8054 (4-[4-(4-Methyl-2-methylaminothiazol-5-yl)pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		70	-9.92	n/a	n/a	n/a	n/a	n/a	n/a	30
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Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM8054 (4-[4-(4-Methyl-2-methylaminothiazol-5-yl)pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM8054 (4-[4-(4-Methyl-2-methylaminothiazol-5-yl)pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		320	-9.00	n/a	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
					More data for this Ligand-Target Pair