BDBM8061 2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 32::4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-(3-nitrophenyl)pyrimidin-2-amine, 4::4-methyl-5-{2-[(3-nitrophenyl)amino]pyrimidin-4-yl}-1,3-thiazol-2-amine::CDK Inhibitor, 1::[4-(2-Amino-4-methylthiazol-5-yl)pyrimidin-2-yl](3-nitrophenyl)amine

SMILES: Cc1nc(N)sc1-c1ccnc(Nc2cccc(c2)N(=O)=O)n1

InChI Key: InChIKey=DYTKVFHLKPDNRW-UHFFFAOYSA-N

Data: 13 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 8061   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2 (Human)	BDBM8061 (4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-(3-nitroph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM8061 (4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-(3-nitroph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM8061 (4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-(3-nitroph...) Show SMILES Show InChI	GoogleScholar	UniChem		<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM8061 (4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-(3-nitroph...) Show SMILES Show InChI	GoogleScholar	UniChem		2	-12.1	n/a	n/a	n/a	n/a	n/a	n/a	30
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Cyclin-T1/Cyclin-dependent kinase 9 (Human)	BDBM8061 (4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-(3-nitroph...) Show SMILES Show InChI	GoogleScholar	UniChem		4	-11.6	n/a	n/a	n/a	n/a	n/a	7.2	30
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Cyclin-dependent kinase 9 (Human)	BDBM8061 (4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-(3-nitroph...) Show SMILES Show InChI	GoogleScholar	UniChem		4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4 (Human)	BDBM8061 (4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-(3-nitroph...) Show SMILES Show InChI	GoogleScholar	UniChem		19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM8061 (4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-(3-nitroph...) Show SMILES Show InChI	GoogleScholar	UniChem		20	-10.7	n/a	n/a	n/a	n/a	n/a	n/a	30
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Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM8061 (4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-(3-nitroph...) Show SMILES Show InChI	GoogleScholar	UniChem		53	-10.1	n/a	n/a	n/a	n/a	n/a	n/a	30
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Cyclin-H/Cyclin-dependent kinase 7 (Human)	BDBM8061 (4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-(3-nitroph...) Show SMILES Show InChI	GoogleScholar	UniChem		70	-9.92	n/a	n/a	n/a	n/a	n/a	7.2	30
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Cyclin-dependent kinase 1 (Human)	BDBM8061 (4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-(3-nitroph...) Show SMILES Show InChI	GoogleScholar	UniChem		73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 7 (Human)	BDBM8061 (4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-(3-nitroph...) Show SMILES Show InChI	GoogleScholar	UniChem		73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM8061 (4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-(3-nitroph...) Show SMILES Show InChI	GoogleScholar	UniChem		80	-9.84	n/a	n/a	n/a	n/a	n/a	7.4	30
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Protein kinase C alpha type (Human)	BDBM8061 (4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-(3-nitroph...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	>-8.32	n/a	n/a	n/a	n/a	n/a	n/a	30
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Casein kinase II subunit alpha (Human)	BDBM8061 (4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-(3-nitroph...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	>-8.32	n/a	n/a	n/a	n/a	n/a	n/a	30
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