BDBM8066 2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 37::4-(dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-1-N,1-N-dimethylbenzene-1,4-diamine, 3::4-N-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-1-N,1-N-dimethylbenzene-1,4-diamine::N-[4-(2,4-Dimethylthiazol-5-yl)pyrimidin-2-yl]N,N-dimethylbenzene-1,4-diamine

SMILES: CN(C)c1ccc(Nc2nccc(n2)-c2sc(C)nc2C)cc1

InChI Key: InChIKey=FGGSNQOBRJVAKL-UHFFFAOYSA-N

Data: 9 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 8066   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2 (Human)	BDBM8066 (4-(dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-1-N,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM8066 (4-(dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-1-N,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM8066 (4-(dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-1-N,1...) Show SMILES Show InChI	GoogleScholar	UniChem		6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM8066 (4-(dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-1-N,1...) Show SMILES Show InChI	GoogleScholar	UniChem		15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM8066 (4-(dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-1-N,1...) Show SMILES Show InChI	GoogleScholar	UniChem		220	-9.23	n/a	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM8066 (4-(dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-1-N,1...) Show SMILES Show InChI	GoogleScholar	UniChem		251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Human)	BDBM8066 (4-(dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-1-N,1...) Show SMILES Show InChI	GoogleScholar	UniChem		575	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM8066 (4-(dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-1-N,1...) Show SMILES Show InChI	GoogleScholar	UniChem		960	-8.34	n/a	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Human)	BDBM8066 (4-(dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-1-N,1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM8066 (4-(dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-1-N,1...) Show SMILES Show InChI	GoogleScholar	UniChem		2.52E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 7 (Human)	BDBM8066 (4-(dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-1-N,1...) Show SMILES Show InChI	GoogleScholar	UniChem		4.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair