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BDBM81183 US10245267, Example 482::US10709712, Example 482::US9694016, 482

SMILES: CC(C)c1cc(ccn1)C(=O)Nc1ccc(C)c(c1)-c1cc(N2CCOCC2)n(C)c(=O)c1

InChI Key: InChIKey=OGIKZKDRUHMPSK-UHFFFAOYSA-N

Data: 6 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 81183   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase B-raf [V600E]


(Human)
BDBM81183
PNG
(US9694016, 482 | US10245267, Example 482 | US10709...)
GoogleScholar
UniChem
n/an/a 0.600n/an/an/an/a7.525


TBA



Citation and Details
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340E,Y341E]


(Human)
BDBM81183
PNG
(US9694016, 482 | US10245267, Example 482 | US10709...)
GoogleScholar
UniChem
n/an/a 0.200n/an/an/an/a7.525


TBA



Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E]


(Human)
BDBM81183
PNG
(US9694016, 482 | US10245267, Example 482 | US10709...)
GoogleScholar
UniChem
n/an/a 0.600n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Human)
BDBM81183
PNG
(US9694016, 482 | US10245267, Example 482 | US10709...)
GoogleScholar
UniChem
n/an/a 0.200n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E]


(Human)
BDBM81183
PNG
(US9694016, 482 | US10245267, Example 482 | US10709...)
GoogleScholar
UniChem
n/an/a 0.600n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Human)
BDBM81183
PNG
(US9694016, 482 | US10245267, Example 482 | US10709...)
GoogleScholar
UniChem
n/an/a 0.200n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair