BDBM8127 N-methyl-N-phenyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine::N-methyl-N-phenyl-4-{pyrazolo[1,5-a]pyridazin-3-yl}pyrimidin-2-amine::pyrazolo[1,5-b]pyridazine deriv. 17

SMILES: CN(c1ccccc1)c1nccc(n1)-c1cnn2ncccc12

InChI Key: InChIKey=XYEFJKRTJUALOK-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 8127   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM8127 (N-methyl-N-phenyl-4-pyrazolo[1,5-b]pyridazin-3-ylp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.99E+4	n/a	n/a	n/a	n/a	7.2	22
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Glycogen synthase kinase-3 beta (Human)	BDBM8127 (N-methyl-N-phenyl-4-pyrazolo[1,5-b]pyridazin-3-ylp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Human)	BDBM8127 (N-methyl-N-phenyl-4-pyrazolo[1,5-b]pyridazin-3-ylp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	186	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Human)	BDBM8127 (N-methyl-N-phenyl-4-pyrazolo[1,5-b]pyridazin-3-ylp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	186	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair